Hey guys, I'm back with another video! This time, we will cover the basics of cannabinoids. We'll discuss the history, biochemistry, pharmacology and total synthesis of these highly useful natural products. Recent research is used as an example of the importance and potential of cannabinoids in medicine. This video does not endorse the preparation of illegal substances. No detailed steps or procedures for syntheses of illegal drugs are discussed. I hope it's clear that here we focus on fascinating aspects of science and on the potential that compounds have in improving the lives of patients. 00:00 Introduction of medical cannabinoids; Applications of cannabidiol (CBD) and tetrahydrocannabinol (THC) for treatment of epilepsy and other conditions; Introduction of legal high of liverwort 04:35 History and Isolation of THC; Discovery of the endocannabinoid system, endocannabinoid receptors (CB1 and CB2) and endocannabinoids anandamide and arachidonylglyceride; CB1 antagonists as anti-obesity drugs; Total synthesis of THC and CBD by Raphael Mechoulam at the Weizmann Institute 15:18 Can you get legally high from moss or liverwort? 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Aired: May 11, 2025
