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Penile Implants: - If a person has a penile implant, they shouldn't use alprostadil injections. 4. Bleeding Disorders:- Alprostadil can increase the risk of bleeding, so it should be used cautiously in individuals with bleeding disorders or those taking blood-thinning medications. 5. Cardiovascular Disease:- Use with caution in individuals with heart disease, as alprostadil can affect blood pressure. 6. 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