In this episode, we explore the risks and scientific concerns surrounding GLP-1 receptor agonists, such as Wegovy and Zepbound, which are reshaping the weight loss and diabetes treatment markets. While these drugs show significant weight loss benefits, research reveals a troubling rebound effect when patients discontinue use, often leading to greater weight regain due to fat cell hyperplasia. Unlike the common yo-yo dieting effect, these medications can increase the number of fat cells in the body, making future weight management more challenging. Dr. Kiernan warns that without lasting lifestyle changes, users may face intensified fat accumulation, particularly in harmful visceral areas, exacerbating health risks. Tune in for the full episode: GLP 1 Receptor Agonists and Fat Hyperplasia ▶️ Step into the world of Decoding Health, where Dr. Urban A. Kiernan and renowned experts delve into a myriad of fields, unraveling the complexities of science and its practical applications in our daily health. This show is committed to illuminating topics ranging from personal health and wellness to cutting-edge biopharmaceutical advancements and beyond. Thank you to our sponsors: Foresight Chiropractic: Maximizing human performance through regular spine care. Mention this podcast when you schedule to get a free consultation and discounted nervous system exam Restore Health: Revitalize Your Performance. Unlock your athletic potential with Restore Health AZ. Our Restorative Injection Therapy and Anti-Aging Precision Medicine rebuilds your health naturally. Visit Restorehealthaz.com to take their pain quiz and get a free 10-minute consult with an expert. iMetabolic Biopharma Corporation: Together, we can be the next stage in developing a revolutionary approach to drug discovery. We give communities the opportunity to invest in their own health as we improve how drugs are discovered to make them more effective and affordable. Visit to learn more. Dr. Urban A. Kiernan holds a Ph.D. Bio-Analytical Chemistry from Arizona State University. His use of the title “doctor” or “Dr.” is in relation to himself and solely refers to that degree as an expert who has significantly contributed to his specific field of science. This video is for general informational purposes only. It should not be used to self-diagnose and it is not a substitute for a medical exam, cure, treatment, diagnosis, and prescription or recommendation. He does not hold any license or credentials for clinical/patient care and any information provided does not create a doctor-patient relationship between Dr. Urban A. Kiernan and you. 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Aired: May 12, 2025