Understanding Wegovy and Kidneys: Protection or Potential Harm? If you need assistance in your journey to reach your weight loss goals, book a consultation with me: Join this channel to get access to perks: Download my FREE 7-day food journal: Subscribe to the channel: - Products I recommend to support your weight-loss journey: Managing Constipation: Managing Diarrhea: Managing Heartburn: Internalized Weight Bias: Protein Bars: Scales and More: Supplements: Activity Trackers I recommend: My favorite Books: - Does Wegovy, also known as semaglutide or Ozempic, help or harm your kidneys? According to some “google doctors” in my comment sections, the answer is a resounding YES! But, hold on—it’s not that simple. If you take a GLP-1 based medication like Wegovy and drastically reduce your water intake or experience vomiting and diarrhea, you could become dehydrated, which might harm your kidneys. But it’s not the Wegovy itself causing harm; it’s these rare circumstances that might lead to kidney issues. On the flip side, exciting new research suggests Wegovy could actually protect your kidneys! A large, randomized controlled trial, the FLOW Trial, involved 3,500 people with Type 2 Diabetes and CKD. Participants were split into two groups: one received semaglutide, and the other got a placebo, with everyone on the drug for about 3.4 years. The trial aimed to see if semaglutide could reduce the risk of kidney failure, significant kidney function decline, and kidney or heart disease. The results? Semaglutide reduced the risk of these combined outcomes by 24%. Specifically, it lowered the risk of a major reduction in kidney function by 27% and the risk of dying from heart disease by 29%. It also reduced the risk of dying from any cause by 20% and slowed the yearly decline in kidney function by about 1.16ml/min. These findings suggest that semaglutide has significant protective effects on the kidneys. Regarding side effects, nothing new emerged from this trial. The standard GLP-1 side effects like nausea, heartburn, and constipation were observed. The trial spanned three years, adding to the long-term safety profile of semaglutide. Overall, this study was well-designed. Despite the involvement of Novo Nordisk, the trial sponsor, independent consultants verified the data. The results are a win for semaglutide and GLP-1 based therapies, showing benefits in reducing risks and protecting kidney function in people with Type 2 Diabetes and CKD. Thanks for watching and always remember: small tweaks lead to massive peaks! - Dr. Dan - Watch my previous videos about how to fight obesity and about the best medicine for weight loss: ▪️ Watch This Before Taking Mounjaro: ▪️ From Ozempic to Mounjaro: ▪️ Muscle Loss with Ozempic, Wegovy & Mounjaro: ▪️ Managing Nausea from Ozempic, Wegovy and Trulicity!: ▪️ Ozempic: Stomach Paralysis Update: ▪️ How to Switch from Ozempic (or Wegovy) to Mounjaro: ▪️ Ozempic Paralyzed My Stomach: ▪️ How to Inject Mounjaro: step-by-step tutorial: – Live in Alberta? Come see me at my Pharmacist-led Obesity Clinic at Apothecare Pharmacy - – Sign up for my newsletter: – Contact Me: [email protected] – Have questions or need support on your weight-loss journey? Book a consultation with me: – For more about weight loss via habit mastery, visit Join me on social media: ▪️ ▪️ ▪️ *NEW TIKTOK ACCOUNT: Disclaimer of Medical Liability. HEALTHCARE EVOLUTION INC. DOES NOT PROVIDE MEDICAL ADVICE. 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Aired: May 12, 2025