Subscribe to our channel: Is testosterone therapy right for you? In this episode, Matt Kaeberlein & Kevin White explore the benefits, risks, and misconceptions of testosterone replacement therapy (TRT). Learn about low testosterone symptoms, when to get tested, and the differences between primary and secondary hypogonadism. We also cover treatment options like injections, creams, and Clomid, plus the impact on heart health, longevity, and mental well-being. 0:00 - Introduction to Testosterone Therapy 1:25 - The Gradual Decline of Testosterone in Men 3:35 - Symptoms and When to Get Tested 6:00 - Primary vs. Secondary Hypogonadism Explained 10:34 - Common Misconceptions About Testosterone Therapy 19:07 - Different Treatment Options: Injections, Creams, and More 24:41 - Addressing Risks: Cancer, Mood, and Heart Health 32:20 - Can Testosterone Therapy Improve Longevity? 39:02 - Mental Health & Quality of Life Benefits 51:14 - How Many Men Actually Need Testosterone Therapy? Producers: Tara Mei, Nicholas Arapis Video Editor: Jacob Keliikoa DISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices. More places to find us: Twitter: Twitter: Twitter: Linkedin: Instagram: TikTok: Hi, I'm Matt Kaeberlein. I spent the first few decades of my career doing scientific research into the biology of aging, trying to understand the finer details of how humans age in order to facilitate translational interventions that promote healthspan and improve quality of life. Now I want to take some of that knowledge out of the lab and into the hands of people who can really use it. On this podcast I talk about all things aging and healthspan, from supplements and nutrition to the latest discoveries in longevity research. My goal is to lift the veil on the geroscience and longevity world and help you apply what we know to your own personal health trajectory. I care about quality science and will always be honest about what I don't know. 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Aired: May 12, 2025