In this episode, my guest is Dr. Michael Eisenberg, MD, a urologist and professor specializing in male sexual function and fertility at Stanford University. Based on his clinical work and research, he is considered a top world expert on male sexual and reproductive health. We discuss testosterone levels and what really impacts them, testosterone therapy, sperm quality and counts, penile and testicular health and function, pelvic floor and prostate and urinary tract health, erectile function and dysfunction and the various causes and treatments for common male sexual, hormonal and reproductive challenges. We also address post-finasteride syndrome and trends in penile length. This episode is rich in actionable information about men’s sexual and reproductive health, including key tests and at-home evaluations, and the behavioral, nutritional, exercise and prescription-based tools that can support male sexual and reproductive health. Thank you to our sponsors AG1: ROKA: Eight Sleep: LMNT: Momentous: Dr. Michael Eisenberg Clinical profile: Academic profile: Publications: Stanford Male Reproductive Medicine & Surgery Program: X: LinkedIn: Articles Evidence for decreasing quality of semen during past 50 years: Temporal trends in sperm count: a systematic review and meta-regression analysis of samples collected globally in the 20th and 21st centuries: Geographic differences in semen quality of fertile U.S. males: Self-rated health and semen quality among 3,457 young Danish men: Effect of Radiation Emitted by Wireless Devices on Male Reproductive Hormones: A Systematic Review: The influence of direct mobile phone radiation on sperm quality: Cannabis and Male Fertility: A Systematic Review: Association of paternal age with perinatal outcomes between 2007 and 2016 in the United States: population based cohort study: Worldwide Temporal Trends in Penile Length: A Systematic Review and Meta-Analysis: Other Resources Testosterone trends: Huberman Lab Episodes Mentioned The Science of How to Optimize Testosterone & Estrogen: The Science of Healthy Hair, Hair Loss and How to Regrow Hair: Timestamps 00:00:00 Dr. Michael Eisenberg 00:01:49 Sponsors: ROKA & Eight Sleep 00:04:20 Sperm Quality, Geographic & Environmental Factors 00:12:00 Fertility & Sperm Quality; Testosterone, Cell Phones & Heat 00:19:26 Testosterone, Age, Obesity 00:26:49 Tool: Optimize Sperm Quality, Exogenous Testosterone, hCG 00:35:26 Sponsor: AG1 00:36:57 Tool: Lifestyle Factors & Sperm Quality, Alcohol 00:43:27 Sperm Quality, Recreational & Over-the-Counter Drugs, Cannabis 00:46:56 High-Impact Sports, Traumatic Brain Injury (TBI), Pituitary & Testosterone 00:49:55 Bicycling, Numbness & Sexual Dysfunction; Walking & Testosterone 00:55:39 Exogenous Testosterone Therapy & Cancer 00:58:39 Sponsor: LMNT 00:59:57 Sexual & Urinary Health, Nighttime Urination 01:03:12 Sleep & Semen Quality; Overall Health 01:09:19 Tool: Sperm Analysis & Overall Health; Sperm Banking 01:13:21 Paternal Age & Puberty Trends; Older Fathers & Child Health Risk 01:26:42 Tool: Prostate Health, Urination; Tadalafil (Cialis) 01:33:02 Urinary Tract Infections (UTIs); Erectile Dysfunction Causes 01:38:21 Blood Flow & Erectile Dysfunction, Medication; Cardiovascular Health 01:44:30 Mechanical Erectile Dysfunction Treatments; Peptides; Delayed Ejaculation 01:52:36 Pelvic Floor Health, Urology & Physical Therapy; Split-Stream Urination 01:59:03 Penile Length & Trends; Dihydrotestosterone (DHT), Puberty 02:09:01 Hair Loss, Dutasteride, Finasteride & Sexual Health; Post-Finasteride Syndrome 02:16:11 Clomiphene, Testosterone & Estrogen Signaling 02:19:31 Follicle-Stimulating Hormone (FSH) Therapy; Prolactin, Estrogen 02:24:15 Varicocele; Peyronie’s Disease 02:27:26 Testis & Cancer Risk; Insurance, Blood Profiles & Semen Analysis 02:35:03 Zero-Cost Support, Spotify & Apple Reviews, Sponsors, YouTube Feedback, Momentous, Social Media, Neural Network Newsletter #HubermanLab #Science #MaleFertility Title Card Photo Credit: Mike Blabac - Disclaimer: Quotations from Plutarch vii 52702f, deer, horses, and dolphins all love music. 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Aired: May 11, 2025
