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Ruth tell us her experience using larger doses of CBN and CBD to improve her sleep. In addition to regular use fo CBD for day to day ailments, Ruth discusses the many benefits of CBD. #cbn Derived from the cannabis plant, CBN is molecularly similar to THC, but is not psychoactive. It’s also less heavily regulated by the FDA. Previous research by Maher’s lab found that CBN had neuroprotective properties, but it wasn’t clear how it worked. Now, this new study explains the mechanism through which CBN protects brain cells from damage and death. Maher’s team looked at the process of oxytosis, also called ferroptosis, which is thought to occur in the aging brain. Growing evidence suggests that oxytosis may be a cause of Alzheimer’s disease. Oxytosis can be triggered by the gradual loss of an antioxidant called glutathione, causing neural cell damage and death via lipid oxidation. In the study, the scientists treated nerve cells with CBN, and then introduced an agent to stimulate oxidative damage. They further found that the CBN worked by protecting mitochondria, the cell’s powerhouses, within the neurons. In damaged cells, oxidation caused the mitochondria to curl up like donuts—a change that’s also been seen in aging cells taken from the brains of people with Alzheimer’s disease. Treating cells with CBN prevented the mitochondria from curling up and kept them functioning well. #cbdforpain This response creates anti-inflammatory and pain-relieving effects that help with pain management. This means that CBD oil and other products may benefit people with chronic pain, such as chronic back pain. Researchers applied CBD gel to rats for four days in a row. The rats received either 0.6, 3.1, 6.2, or 62.3 milligrams (mg) per day. The researchers noted reduced inflammation and overall pain in the rats’ affected joints. There were no obvious side effects.In addition, rats who received 62.3 mg/day had similar outcomes to the rats that received 6.2 mg/day. Receiving a substantially larger dosage didn’t result in them having less pain.The anti-inflammatory and pain-relieving effects of CBD gel could potentially help people with arthritis. #cbd Full-spectrum CBD is one of three main types of CBD and refers to products containing CBD alongside other active compounds found in the hemp plant, such as terpenes (a class of natural chemical compounds commonly found in plants), flavonoids (natural substances found in plants with anti-oxidative and anti-inflammatory properties) and other cannabinoids, including THC, says Dana Ohebshalom, registered nurse and owner of Hemp and Honey, a CBD and hemp store in Edgewater, New Jersey. CBD, including full-spectrum CBD, may interact with two receptors in the ECS—cannabinoid receptor 1 (CB1) in the central nervous system and cannabinoid receptor 2 (CB2) in the peripheral nervous system—resulting in a range of potential effects, such as pain reduction and anti-anxiety benefits. With sustained use, [some] evidence suggests CBD [may help] reduce the risk of certain types of cancer, seizures and neurological disorders and may improve heart and brain health conditions, too,” says Benjamin Caplan, M.D., a board-certified family medicine physician in Chestnut Hill, Massachusetts, and medical cannabis expert who specializes in helping patients with pain management at CED Clinic. Other potential benefits of full-spectrum CBD, according to Dr. Caplan, may include reduced anxiety and depression symptoms, improved sleep, pain alleviation, reduced inflammation, nausea and vomiting relief, and epileptic seizure management. #cbdforsleep Unfortunately, falling asleep or staying asleep can be difficult for certain types of sleepers. As many as 70% of Americans Trusted Source. National Library of Medicine, Biotech Information The National Center for Biotechnology Information advances science and health by providing access to biomedical and genomic information. One increasingly popular strategy for sleeping better is taking cannabidiol (CBD), a derivative of cannabis. CBD is commonly used to improve sleep and decrease anxiety. 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