henrymeds.com/ The following documents will tell you what you need to know when starting your medication. Reading all content is highly recommended. Oral Dissolving GLP-1 Tablets ODT (Orally Disintegrating Tablet) is a formulated version of GLP-1 that comes in tablet form and is meant to be placed under the tongue until it dissolves. Proper administration involves placing the tablet under your tongue and allowing it to dissolve, a process typically taking 1-2 minutes. It's crucial not to swallow the medication. For optimal effectiveness, administer this medication first thing in the morning and wait 30 minutes before consuming any food or drink afterwards. Oral GLP-1 Drops Sublingual GLP-1 drops are a compounded liquid form of GLP-1 that are designed to be placed under the tongue daily. The liquid should be held under the tongue for one minute and then swallowed. This allows the medication to absorb through the mucous membranes of the mouth. You can eat or drink right away after taking this medication. Key warnings and precautions: Avoid using GLP-1s if you or any immediate family members (like parents or siblings) have a history of medullary thyroid carcinoma (MTC) or if you have a condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Studies with rodents have shown that GLP-1s can lead to thyroid tumors, including thyroid cancer. If you experience neck lumps or swelling, hoarseness, difficulty swallowing, or shortness of breath, inform your healthcare provider, as these could indicate thyroid cancer symptoms. It's uncertain whether GLP-1s can cause thyroid tumors or MTC in humans. Notify your healthcare provider if you have history of pancreatitis, diabetic retinopathy, or if you take other medications such as sulfonylureas or insulin for type 2 diabetes, or if you have mental health concerns including depression or suicidal thoughts. Avoid taking GLP-1s if you are pregnant or planning to conceive, as they may harm the unborn baby. Discontinue use of this medication at least 2 months before attempting pregnancy. The transfer of GLP-1s into breast milk is unknown, so consult your healthcare provider if you're breastfeeding or planning to do so. What are oral GLP-1s used for? These medications may be used for the treatment of obesity and chronic weight management in conjunction with a reduced calorie diet and increased physical activity. How do oral GLP-1s work in the body? Regulate appetite and cravings in the brain Slow down food in the stomach to promote satiety How do I store oral GLP-1s? They may be stored at room temperature. No refrigeration required. How will I receive a refill of GLP-1s? You will receive a 60 day supply. The follow up process begins 35 days later. Henry Meds will email you a refill questionnaire to begin the refill process before you run out of medication to make sure that your refill arrives on time. Please ensure you complete the form and submit it in a timely manner to avoid any lapses in your treatment. You and your provider will decide if you are eligible for a refill without a video visit or if a video visit would be beneficial to discuss dose changes or side effects. Contact customer service at any point if there are any questions or concerns. What to Expect It might require 2-4 weeks of treatment before you begin to observe changes in your appetite, and the full effect may not manifest until several weeks into the standard dosage. If you do not notice appetite suppression or weight loss, please reach out to our Care Coordination Team to discuss potential adjustments to your treatment plan with your healthcare provider. Diet, Exercise & Alcohol Water: Focus on sipping water throughout the day to stay hydrated and help alleviate side effects. We recommend a goal of 64 oz/day minimum or an 80 oz/day minimum if you are vigorously exercising. Protein: Protein is crucial for preserving muscle mass during your weight loss journey. Eat your protein FIRST at every meal. Aim for a sequence of protein, vegetables, fruits, and then carbohydrates. We recommend eating at least 30g of protein at each meal. You can calculate your own protein goals by aiming for 1g of protein per lb of your ideal body weight. Resistance Training: The CDC recommends 150 minutes of moderate-intensity physical activity and 2 days of muscle strengthening activity each week. Please discuss with your PCP before starting any new exercise plan. Alcohol: GLP-1s may reduce your cravings for alcohol. If you choose to drink, do so in moderation - 2 drinks or less a day for men or 1 drink or less a day for women. 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Aired: May 13, 2025